Doctor Discussion Guide
Doctor Discussion Guide
Doctor Discussion Guide Be prepared to talk with a doctor about CPP and your child. Take our Doctor Discussion Guide with you to your pediatrician visit to help you get the answers you need.
Parent Survey
Growth Comparison Tool
Parent Survey How does your child compare to other children with central precocious puberty (CPP)? Take our interactive Parent Survey and get a better understanding of the condition.
Diagnosis and Treatment
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Diagnosis and Treatment for Your Child

Knowing as much as possible about central precocious puberty (CPP) diagnosis and treatment can help you prepare your child for what to expect during a visit to the doctor to diagnose the condition. Below, you will find information on tests your pediatrician or pediatric endocrinologist may perform to diagnose CPP and facts about Lupron Depot-PED, a hormonal therapy he or she may recommend to treat the condition.

Diagnosing CPP

Generally, your doctor begins diagnosis of CPP with a detailed physical examination of your child, usually followed by a series of tests, including some or all of the following:

  • An x-ray of the hand and wrist

    Helps the doctor to determine if the bone age (bone development) of your child is older than your child's chronological age. Bone age can help your doctor decide whether your child has central precocious puberty or not.

  • A blood test

    Performed to determine the level of various hormones in your child's bloodstream

  • A GnRH stimulation test

    Checks to see if the cause of increased hormones in your child's bloodstream is coming from the brain. If it is, that is a sign that your child has CPP.

  • A pelvic and adrenal ultrasound

    Looks for abnormalities of the ovaries, adrenals, and testicles

  • A magnetic resonance imaging (MRI) or computerized axial tomography (CAT) scan

    Taken of your child's head to show any abnormalities in the pituitary gland or the hypothalamus

Treating CPP

Once tests are complete, the doctor will look at the results, make a diagnosis, and discuss possible courses of treatment with you, that may include treatment with Lupron Depot-PED.

Therapy with Lupron Depot-PED

Lupron Depot-PED therapy stops your child's body from making certain hormones. By adjusting your child's body clock, it delays puberty until a more appropriate time in your child's life.

Lupron Depot-PED is administered as an injection on a monthly basis. Discontinuation of Lupron Depot-PED should be considered before age 11 for girls and age 12 for boys.
See below for important safety and other information on Lupron Depot-PED.
All photos are of models and not of users of Lupron Depot-PED or persons suffering symptoms described.
    

Important Safety and Other Information:

Lupron Depot-PED (7.5 mg, 11.25 mg, and 15 mg) is used for the treatment of central precocious puberty. In clinical studies, the most frequent adverse event related to therapy with Lupron Depot-PED was an injection site reaction, seen in 5% of children in the combined studies. The recommended starting dose of Lupron Depot-PED is 0.3 mg/kg/4 weeks (minimum 7.5 mg). Inadequate dosing may result in poor control of the pubertal process.

For further information about Lupron Depot-PED, please see the complete Prescribing Information, as well as the
Patient Product Information.
  
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