Doctor Discussion Guide
Doctor Discussion Guide
Doctor Discussion Guide Be prepared to talk with a doctor about CPP and your child. Take our Doctor Discussion Guide with you to your pediatrician visit to help you get the answers you need.
Growth Comparison Tool
Growth Comparison Tool
Growth Comparison Tool How does your child compare to other children of the same age? Use our Growth Comparison Tool to track one observable aspect of your child's growth—his or her height.
Central Precocious Puberty
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Learn About Symptoms and Causes

In order for you to take an active role in your child's treatment for central precocious puberty (CPP), you need reliable information. Below we provide an overview on CPP and its possible symptoms and causes. If you have any further questions, please speak with your doctor.

What is CPP?

Central precocious puberty is a condition in which puberty starts too soon in children. This occurs in one child of every 5,000 to 10,000 children and is more common in girls.

During puberty, the brain releases a hormone called gonadotropin-releasing hormone (GnRH), which in turn stimulates a child's sex hormone production, sexual development, and physical growth. For girls, this means the growth and maturation of the ovaries. For boys, this means the growth and maturation of the testicles. Changes for both sexes during puberty include the appearance of pubic and underarm hair, and a rapid increase in height.

With central precocious puberty, the sex hormones are released early, causing the body changes that go along with the release to happen early as well.

Signs and symptoms of CPP

When they occur too soon, the following signs and symptoms may indicate CPP:
  • Girls develop breasts and may have monthly periods
  • The penis and testicles of boys grow larger, and erections can occur
  • Behavior may change; children may become aggressive or moody
  • Pubic hair grows in both sexes
  • Children may have oily skin and/or acne
  • There is a sudden growth spurt like that usually seen in teenagers; your child may be the tallest in the class but their eventual adult height may be shorter than normal

Causes of CPP

In most cases, there is no special reason for your child's early development. It is not caused by anything you do and is not necessarily passed on from parents to children. Your doctor will perform tests to identify a possible physical cause of CPP.

Read on to learn how CPP is diagnosed by a doctor, and find out about possible treatment with Lupron Depot-PED.
See below for important safety and other information on Lupron Depot-PED.
All photos are of models and not of users of Lupron Depot-PED or persons suffering symptoms described.
    

Important Safety and Other Information:

Lupron Depot-PED (7.5 mg, 11.25 mg, and 15 mg) is used for the treatment of central precocious puberty. In clinical studies, the most frequent adverse event related to therapy with Lupron Depot-PED was an injection site reaction, seen in 5% of children in the combined studies. The recommended starting dose of Lupron Depot-PED is 0.3 mg/kg/4 weeks (minimum 7.5 mg). Inadequate dosing may result in poor control of the pubertal process.

For further information about Lupron Depot-PED, please see the complete Prescribing Information, as well as the
Patient Product Information.
  
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